3-Ethoxy-2,6-difluorobenzaldehyde synthesis
- Product Name:3-Ethoxy-2,6-difluorobenzaldehyde
- CAS Number:1028263-18-4
- Molecular formula:C9H8F2O2
- Molecular Weight:186.16
367-27-1
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$6.00/5g
1028263-18-4
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$75.00/100mg
Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: K2CO3 / acetone / 55 °C
2.1: n-BuLi / hexane; tetrahydrofuran / 0.5 h / -65 °C
2.2: hexane; tetrahydrofuran / -65 - 20 °C
References:
H?gberg, Marita;Sahlberg, Christer;Engelhardt, Per;Noréen, Rolf;Kangasmets?, Jussi;Johansson, Nils Gunnar;?berg, Bo;Vrang, Lotta;Zhang, Hong;Sahlberg, Britt-Louise;Unge, Torsten;L?vgren, Seved;Fridborg, Kerstin;B?ckbro, Kristina [Journal of Medicinal Chemistry,1999,vol. 42,# 20,p. 4150 - 4160]