天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 3-Chloro-5-(trifluoromethyl)pyridine
85148-26-1

3-Chloro-5-(trifluoromethyl)pyridine synthesis

3synthesis methods
-

Yield: 7%

Reaction Conditions:

with acetic acid;zinc in water at 90; for 1.25 h;

Steps:

7
Add zinc dust (1. 18 g) to a suspension of 2, 3-dichloro-5-trifluoromethyl-pyridine (2. 0 g, 9. 30 mmol) in 80 : 20 water and acetic acid (5 mL) and stir at 90 °C for 1 h. Add more zinc dust (1 g) and stir at 90 °C for an additional 15 min. Cool the reaction mixture to room temperature, filter, and wash with dichloromethane. Carefully concentrate and purify the residue by silica gel chromatography, eluting with 100 : 0 to 0 : 100 hexane : dichloromethane, to obtain the title compound as a volatile oil (0. 120g, 7%). 1H NMR (300 MHz, CDCl3) 8 7. 93 (s, 1 H), 8. 78 (s, 2 H). GC-MS (EI) m/z = 181. 0, 183. 0 [M].

References:

ELI LILLY AND COMPANY WO2005/94822, 2005, A1 Location in patent:Page/Page column 28

80289-91-4 Synthesis
2,5,6-TRICHLORO-3-TRIFLUOROMETHYLPYRIDINE

80289-91-4
37 suppliers
inquiry

3796-23-4 Synthesis
3-Trifluoromethylpyridine

3796-23-4
220 suppliers
$7.00/1g

65753-47-1 Synthesis
2-Chloro-3-(trifluoromethyl)pyridine

65753-47-1
374 suppliers
$8.00/5g

70158-59-7 Synthesis
2,5-DICHLORO-3-(TRIFLUOROMETHYL)PYRIDINE

70158-59-7
85 suppliers
$31.00/100mg

3-Chloro-5-(trifluoromethyl)pyridine Related Search: