3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE synthesis

2synthesis methods

Product Name:3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE
CAS Number:354813-00-6
Molecular formula:C11H9FN2OS
Molecular Weight:236.27

METHYL 3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXYLATE

175137-08-3
70 suppliers
$21.21/250mgs:

3-AMINO-5-(4-FLUOROPHENYL)THIOPHENE-2-CARBOXAMIDE

354813-00-6
31 suppliers
$22.00/250mg

Yield:-

Steps:

Multi-step reaction with 3 steps
1: aq. NaOH / methanol
2: SOCl₂
3: NH₃ / acetonitrile

References:

Baxter, Andrew;Brough, Steve;Cooper, Anne;Floettmann, Eike;Foster, Steve;Harding, Christine;Kettle, Jason;McInally, Tom;Martin, Craig;Mobbs, Michelle;Needham, Maurice;Newham, Pete;Paine, Stuart;St-Gallay, Steve;Salter, Sylvia;Unitt, John;Xue, Yafeng [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 11,p. 2817 - 2822]

3-amino-5-(4-fluorophenyl)thiophene-2-carboxylic acid

187949-92-4
3 suppliers
inquiry

354813-00-6
31 suppliers
$22.00/250mg

References