ChemicalBook CAS DataBase List 3,5-Dinitrobenzoyl chloride

3,5-Dinitrobenzoyl chloride synthesis

4synthesis methods

Product Name:3,5-Dinitrobenzoyl chloride
CAS Number:99-33-2
Molecular formula:C7H3ClN2O5
Molecular Weight:230.56

99-34-3 Synthesis

99-34-3
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99-33-2
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$12.00/5g

Yield:99-33-2 95%

Reaction Conditions:

with thionyl chloride in tolueneReflux;

Steps:

procedure for the preparation of aromatic carboxylic acid chlorides
General procedure: The appropriate aromatic carboxylic acid (0.01 mol), thionyl chloride SOCl₂ (1.6 mL, 0.02mol) and a dry toluene (40 mL) were heated at reflux until the disappearance of the carboxylic acid was fully completed (TLC; 2-8 h). After cooling, the mixture was concentrated on a rotary evaporator. The crude products were distilled under reduced pressure to yield the adequate pure acid chlorides (3a-h).

References:

Kudelko, Agnieszka;Wróblowska, Monika [Tetrahedron Letters,2014,vol. 55,# 21,p. 3252 - 3254] Location in patent:supporting information

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