3,5-DICHLORO-4-METHOXYBENZOIC ACID ETHYL ESTER synthesis
1synthesis methods
- Product Name:3,5-DICHLORO-4-METHOXYBENZOIC ACID ETHYL ESTER
- CAS Number:15945-28-5
- Molecular formula:C10H10Cl2O3
- Molecular Weight:249.09
Yield:15945-28-5 94%
Reaction Conditions:
Stage #1: ethyl 3,5-dichloro-4-hydroxybenzoatewith potassium carbonate in N,N-dimethyl-formamide at 20;Inert atmosphere;
Stage #2: methyl iodide in N,N-dimethyl-formamide at 20;Inert atmosphere;
References:
Grimster, Neil P.;Connelly, Stephen;Baranczak, Aleksandra;Dong, Jiajia;Krasnova, Larissa B.;Sharpless, K. Barry;Powers, Evan T.;Wilson, Ian A.;Kelly, Jeffery W. [Journal of the American Chemical Society,2013,vol. 135,# 15,p. 5656 - 5668] Location in patent:supporting information