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ChemicalBook CAS DataBase List 3,4-Dihydroxyphenylacetic acid
102-32-9

3,4-Dihydroxyphenylacetic acid synthesis

10synthesis methods
-

Yield:102-32-9 99.7%

Reaction Conditions:

with ascorbic acid in aq. phosphate buffer at 25;

Steps:

2.5. Reaction to produce 3,4-dihydroxyphenylacetic acid (DHPAA) from 4-hydroxyphenylacetic acid (HPAA)
A typical reaction was started by addition of 15.0 mg of tyrosinaseCLEAs into 20.0 mL of Na phosphate buffer (50 mM, pH 6.0) containing10.0mM HPAA and 15.0mM L-ascorbic acid in a 50 mL conical flask,which was placed in a shaking incubator with agitation of 200 rpm at25 °C. Periodically, a 0.15 mL sample was taken which was then fourtimes diluted with the buffer before subjected to HPLC analysis as describedbelow.

References:

Cheng, Hui;Zou, Yong;Luo, Xiang;Song, Xian-Heng;Yang, Zhen [Process Biochemistry,2018,vol. 70,p. 90 - 97]

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