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ChemicalBook CAS DataBase List 3,4-Dichloro-2-fluoropyridine
851179-03-8

3,4-Dichloro-2-fluoropyridine synthesis

2synthesis methods
1480-64-4 Synthesis
3-Chloro-2-fluoro-pyridine

1480-64-4
188 suppliers
$15.00/1g

3,4-Dichloro-2-fluoropyridine

851179-03-8
35 suppliers
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Yield:851179-03-8 80%

Reaction Conditions:

Stage #1: 3-chloro-2-fluoropyridinewith n-butyllithium in tetrahydrofuran;hexane at -75; for 2 h;
Stage #2: with 1,1,2-Trichloro-1,2,2-trifluoroethane in tetrahydrofuran;hexane at -75; for 1 h;

References:

Bobbio, Carla;Rausis, Thierry;Schlosser, Manfred [Chemistry - A European Journal,2005,vol. 11,# 6,p. 1903 - 1910]

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