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ChemicalBook CAS DataBase List [3-(2-METHOXY-PHENYL)-ISOXAZOL-5-YL]-METHANOL
345967-78-4

[3-(2-METHOXY-PHENYL)-ISOXAZOL-5-YL]-METHANOL synthesis

5synthesis methods
-

Yield:345967-78-4 81%

Reaction Conditions:

Stage #1: 2-Methoxy-benzaldehyde oximewith pyridine;N-chloro-succinimide in tetrahydrofuran at 20 - 60; for 1 h;Inert atmosphere;
Stage #2: propargyl alcoholwith triethylamine in tetrahydrofuran at 50; for 3 h;Inert atmosphere;

References:

Landge, Kamalkishor P.;Oh, Ji Seon;Pae, Ae Nim;Park, Woo Kyu;Gong, Jae Yang;Koh, Hun Yeong;Jung, Sun Ho [Bulletin of the Korean Chemical Society,2011,vol. 32,# 7,p. 2449 - 2452] Location in patent:experimental part

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