(2S,4R)-BOC-4-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID synthesis

10synthesis methods

Product Name:(2S,4R)-BOC-4-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID
CAS Number:336818-78-1
Molecular formula:C16H21NO4
Molecular Weight:291.34

(S)-1-tert-Butyl 2-methyl 4-(((trifluoromethyl)-sulfonyl)oxy)-1H-pyrrole-1,2(2H,5H)-dicarboxylate

462125-00-4
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$501.93/5MG

(2S,4R)-BOC-4-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID

336818-78-1
58 suppliers
$80.00/25mg

Yield:-

Steps:

Multi-step reaction with 3 steps
1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / water; 1,4-dioxane / 0.33 h / 80 °C
2: hydrogenchloride / 1,4-dioxane / 0.5 h
3: hydrogen; palladium 10% on activated carbon / ethanol

References:

Kl?ck, Cornelius;Herrera, Zachary;Albertelli, Megan;Khosla, Chaitan [Journal of Medicinal Chemistry,2014,vol. 57,# 21,p. 9042 - 9064]

1,2-Pyrrolidinedicarboxylic acid, 4-phenyl-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-

336818-16-7
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336818-78-1
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References

74844-91-0 Synthesis

N-Boc-trans-4-Hydroxy-L-proline methyl ester

74844-91-0
410 suppliers
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336818-78-1
58 suppliers
$80.00/25mg

References

102195-80-2 Synthesis

102195-80-2
237 suppliers
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336818-78-1
58 suppliers
$80.00/25mg

References

1H-Pyrrole-1,2-dicarboxylic acid, 2,3-dihydro-4-phenyl-, 1-(1,1-dimethylethyl) 2-methyl ester, (S)- (9CI)

174905-43-2
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336818-78-1
58 suppliers
$80.00/25mg

References

(2S,4R)-BOC-4-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID Related Search:

(2S,4S)-N-Boc-4-methylpyrrolidine-2-carboxylic acid