4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID synthesis
- Product Name:4-METHYL-2-(2-PYRAZINYL)-1,3-THIAZOLE-5-CARBOXYLIC ACID
- CAS Number:216959-92-1
- Molecular formula:C9H7N3O2S
- Molecular Weight:221.24
22900-83-0
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216959-92-1
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) chloride / N,N-dimethyl-formamide / 0.5 h / 100 °C / Inert atmosphere; Microwave irradiation
2: lithium hydroxide monohydrate; water / tetrahydrofuran / 16 h / 23 °C
References:
WO2015/161928,2015,A1