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ChemicalBook CAS DataBase List 2-(Trifluoromethoxy)benzyl bromide
198649-68-2

2-(Trifluoromethoxy)benzyl bromide synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium tetrahydroborate / methanol / 0 °C
2.1: methanesulfonyl chloride; triethylamine / tetrahydrofuran
2.2: 1 h / 0 °C

References:

Doebelin, Christelle;Patouret, Rémi;Garcia-Ordonez, Ruben D.;Chang, Mi Ra;Dharmarajan, Venkatasubramanian;Kuruvilla, Dana S.;Novick, Scott J.;Lin, Li;Cameron, Michael D.;Griffin, Patrick R.;Kamenecka, Theodore M. [ChemMedChem,2016,vol. 11,# 23,p. 2607 - 2620]

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