2-Methyl-2-butanol synthesis
- Product Name:2-Methyl-2-butanol
- CAS Number:75-85-4
- Molecular formula:C5H12O
- Molecular Weight:88.15
115-19-5
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75-85-4
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$9.00/10ml
Yield:75-85-4 90%
Reaction Conditions:
with sodium tetrahydroborate;hydrogen;nickel dichloride in isopropyl alcohol at 60; under 760.051 Torr; for 7 h;
Steps:
Ethylbenzene (2a).
General procedure: Anhydrous NiCl2 (1 g, 0.008 mol) was gradually added to a suspension of sodium borohydride (0.6 g, 0.017 mol) in 20 mL of anhydrous isopropanol at vigorous stirring; black colloid solution was formed. Then hydrogen was bubbled through the mixture, and phenylacetylene 1a (15 g, 0.147 mol) was added to the mixture. The reaction mixture was stirredat 60°C for 8 h. After the reaction completion the mixture was cooled, and water (1 mL) was added to accelerate the catalyst coagulation. The precipitate was filtered off, the organic layer was separated, and isopropanol was distilled off. The residue was distilled at atmospheric pressure. Yield 14.8 g (0.14 mol, 95%), bp 134-136° (bp 136° [17]).
References:
Popov, Yu. V.;Mokhov;Nebykov [Russian Journal of General Chemistry,2016,vol. 86,# 1,p. 43 - 45][Zh. Obshch. Khim.,2016,vol. 86,# 1,p. 47 - 50]
6689-16-3
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75-85-4
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115-18-4
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75-85-4
340 suppliers
$9.00/10ml
115-19-5
267 suppliers
$17.00/25mL
75-85-4
340 suppliers
$9.00/10ml
115-18-4
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78-78-4
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75-85-4
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64-19-7
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67-64-1
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