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ChemicalBook CAS DataBase List 2-hydroxy-4-phenylbutyric acid
4263-93-8

2-hydroxy-4-phenylbutyric acid synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 1) LDA / 1) THF, -60 deg C, 10 min
2: 89 percent / xylene / Heating
3: 1) ozone, 2) dimethyl sulfide, water / 1) acetone, -60 deg C, 2) room temperature

References:

Satoh, Tsuyoshi;Onda, Ken-ichi;Yamakawa, Koji [Journal of Organic Chemistry,1991,vol. 56,# 13,p. 4129 - 4134]