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31032-94-7

2-Ethyl-3-methylnaphthalene synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: toluene / 12 h / 110 °C
2.1: HCl / methanol / 20 °C
3.1: LDA / tetrahydrofuran / 1 h / -78 °C
3.2: tetrahydrofuran / -78 - 0 °C
4.1: PTSA / tetrahydrofuran

References:

Kraus, George A.;Choudhury, Prabir K. [Synlett,2004,# 1,p. 97 - 98]