2-CYANO-N-CYCLOHEXYL-ACETAMIDE synthesis

6synthesis methods

Product Name:2-CYANO-N-CYCLOHEXYL-ACETAMIDE
CAS Number:15029-38-6
Molecular formula:C9H14N2O
Molecular Weight:166.22

108-91-8 Synthesis

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105-56-6
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15029-38-6
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$28.60/50MG

Yield:15029-38-6 90%

Reaction Conditions:

with sodium ethanolate in ethanol at 20; for 1 h;

Steps:

4.2. General procedure 1: synthesis of cyanoacetamides 2a-d

General procedure: A mixture of a solution of sodium ethoxide (0.1 mmol) in ethanol (3 mL), ethyl cyanoacetate (10 mmol) and amine (10 mmol) was stirred at room temperature. The reaction time is 1 h for primary amines and 24 h for secondary amine 2d. The precipitate obtained was separated by filtration, washed with diethylether and recrystallised in ethanol to provide a white solid of cyanoacetamides.

References:

Cheikh, Nawel;Bar, Nathalie;Choukchou-Braham, Nourredine;Mostefa-Kara, Bachir;Lohier, Jean-Franois;Sopkova, Jana;Villemin, Didier [Tetrahedron,2011,vol. 67,# 8,p. 1540 - 1551] Location in patent:experimental part

108-91-8 Synthesis

108-91-8
609 suppliers
$10.00/5mL