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ChemicalBook CAS DataBase List 2-(CHLOROMETHYL)-5-(TRIFLUOROMETHYL)PYRIDINE
128790-14-7

2-(CHLOROMETHYL)-5-(TRIFLUOROMETHYL)PYRIDINE synthesis

4synthesis methods
-

Yield:128790-14-7 86%

Reaction Conditions:

with 1,3,5-trichloro-2,4,6-triazine in dichloromethane;N,N-dimethyl-formamide at 20; for 60 h;Reflux;

References:

Thompson, Andrew M.;Sutherland, Hamish S.;Palmer, Brian D.;Kmentova, Iveta;Blaser, Adrian;Franzblau, Scott G.;Wan, Baojie;Wang, Yuehong;Ma, Zhenkun;Denny, William A. [Journal of Medicinal Chemistry,2011,vol. 54,# 19,p. 6563 - 6585] Location in patent:supporting information; experimental part

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