2-chloro-4-piperidinobenzenecarboxylic acid synthesis
- Product Name:2-chloro-4-piperidinobenzenecarboxylic acid
- CAS Number:313674-11-2
- Molecular formula:C12H14ClNO2
- Molecular Weight:239.7
313674-08-7
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$181.00/500mg
313674-11-2
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$244.00/500mg
Yield:313674-11-2 88%
Reaction Conditions:
Stage #1: 2-chloro-4-(piperidin-1-yl)benzoic acid methyl esterwith sodium hydroxide;water in methanol; for 0.75 h;Reflux;
Stage #2: with hydrogenchloride in methanol;water;
References:
Tsukamoto, Issei;Koshio, Hiroyuki;Akamatsu, Seijiro;Kuramochi, Takahiro;Saitoh, Chikashi;Yatsu, Takeyuki;Yanai-Inamura, Hiroko;Kitada, Chika;Yamamoto, Eisaku;Sakamoto, Shuichi;Tsukamoto, Shin-ichi [Bioorganic and Medicinal Chemistry,2008,vol. 16,# 21,p. 9524 - 9535] Location in patent:experimental part
85953-29-3
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$6.00/1g
313674-11-2
13 suppliers
$244.00/500mg