ChemicalBook CAS DataBase List 2-Bromo-N-methylacetanilide

2-Bromo-N-methylacetanilide synthesis

5synthesis methods

Product Name:2-Bromo-N-methylacetanilide
CAS Number:29182-97-6
Molecular formula:C9H10BrNO
Molecular Weight:228.09

598-21-0
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$10.00/10g

100-61-8 Synthesis

100-61-8
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$8.00/1g

29182-97-6
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$45.00/50mg

Yield:29182-97-6 100%

Reaction Conditions:

with triethylamine in ethyl acetate at 0 - 25; for 0.5 h;

Steps:

33

Reference Example 33 2-Bromo-N-methyl-N-phenylacetamide To a solution of N-methylaniline (1.90 mL, 17.5 mmol) and triethylamine (2.44 mL, 17.5 mmol) in ethyl acetate (40 mL) is added a solution of bromoacetyl bromide (1.52 mL, 17.5 mmol) in ethyl acetate (40 mL) at 0°C, and the mixture is stirred at 20-25°C for 30 minutes. After the reaction, the mixture is filtered, and the solvent is evaporated under reduced pressure to give 2-bromo-N-methyl-N-phenylacetamide (4.60 g, quantitative). IR (cm^-1): 1109, 1375, 1593, 1624, 1683

References:

EP1719761,2006,A1 Location in patent:Page/Page column 33