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ChemicalBook CAS DataBase List 2-broMo-4-Methoxy-1-(MethoxyMethoxy)benzene
195314-47-7

2-broMo-4-Methoxy-1-(MethoxyMethoxy)benzene synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: 74 percent / bromine / CHCl3 / 0 - 20 °C
2.1: NaH / dimethylformamide / 0.5 h / 20 °C
2.2: 71 percent / dimethylformamide / 0 - 20 °C

References:

Clark, Richard F.;Zhang, Tianyuan;Wang, Xiaojun;Wang, Rongqi;Zhang, Xiaolin;Camp, Heidi S.;Beutel, Bruce A.;Sham, Hing L.;Gu, Yu Gui [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 7,p. 1961 - 1965]