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ChemicalBook CAS DataBase List 2-Amino-6-chlorobenzaldehyde
35490-90-5

2-Amino-6-chlorobenzaldehyde synthesis

5synthesis methods
-

Yield:35490-90-5 96%

Reaction Conditions:

with manganese(IV) oxide in diethyl ether; for 0.5 h;

Steps:

10

To prepare this compound, manganese dioxide (13.6 g, 157 mmol) was added to a solution of 2-(amino-6-chlorophenyl)methanol (2.75 g, 17.5 mmol) in 150 mL diethyl ether. The mixture was stirred for 0.5 hours then filtered through celite and rinsed with ethyl acetate. The filtrate was concentrated under reduced pressure to afford 2.62 g(96%) of 2-amino-6-chlorobenzaldehyde.

References:

WO2006/10142,2006,A2 Location in patent:Page/Page column 70; 71