ChemicalBook CAS DataBase List 2-amino-6-bromobenzonitrile

2-amino-6-bromobenzonitrile synthesis

9synthesis methods

Product Name:2-amino-6-bromobenzonitrile
CAS Number:77326-62-6
Molecular formula:C7H5BrN2
Molecular Weight:197.03

79544-27-7 Synthesis

79544-27-7
190 suppliers
$10.00/5g

77326-62-6
114 suppliers
$6.00/250mg

Yield: 96%

Reaction Conditions:

with ammonia in dimethyl sulfoxide at 80 - 120;

Steps:

1.3; 2.3 (3) Re-pass ammonia reaction:
_{Add 100 g of 2-fluoro-6-bromobenzonitrile and 400 mL of solvent DMSO to the reaction vessel, stir,Increase the temperature, control the temperature at 80-120 degrees, pass ammonia, and GC tracking until the reaction is completed.After the completion of the reaction, it was separated by water and filtered with suction to obtain 97 g of brown solid 6-amino-2-bromobenzonitrile.The purity is 98%, and the yield is 96%.}

References:

Ningxia University;Yang Jinhui;Wang Shihaozhi;Chen Xingquan;Dong Yanmin CN111548276, 2020, A Location in patent:Paragraph 0018; 0021; 0026; 0029

79603-02-4 Synthesis