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ChemicalBook CAS DataBase List 2-amino-2-(5-bromo-2-fluorophenyl)propanoic acid
1266784-23-9

2-amino-2-(5-bromo-2-fluorophenyl)propanoic acid synthesis

6synthesis methods
rac-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionitrile

1350523-51-1
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2-amino-2-(5-bromo-2-fluorophenyl)propanoic acid

1266784-23-9
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Yield:1266784-23-9 68%

Reaction Conditions:

with hydrogenchloride;acetic acid in water; for 16 h;Reflux;

References:

Rombouts, Frederik J. R.;Tresadern, Gary;Delgado, Oscar;Martínez-Lamenca, Carolina;Van Gool, Michiel;García-Molina, Aránzazu;Alonso De Diego, Sergio A.;Oehlrich, Daniel;Prokopcova, Hana;Alonso, José Manuel;Austin, Nigel;Borghys, Herman;Van Brandt, Sven;Surkyn, Michel;De Cleyn, Michel;Vos, Ann;Alexander, Richard;Macdonald, Gregor;Moechars, Dieder;Gijsen, Harrie;Trabanco, Andrés A. [Journal of Medicinal Chemistry,2015,vol. 58,# 20,p. 8216 - 8235]

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