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ChemicalBook CAS DataBase List 2,8-Quinolinediol
15450-76-7

2,8-Quinolinediol synthesis

9synthesis methods
-

Yield:15450-76-7 85%

Reaction Conditions:

with aluminum (III) chloride in chlorobenzene at 110; for 0.5 h;Temperature;

Steps:

3.2 Example 3

(2) Add 10 g of intermediate 1 to a 250 ml reaction flask, add 100 ml of chlorobenzene, add 20.2 g of AlCl 3 , stir for 30 min, raise the temperature to 110° C., control the reaction, and after the reaction is completed, concentrate under reduced pressure, cool, and filter. Obtain 5.5g intermediate 2, yield 85%;

References:

CN107629000,2018,A Location in patent:Paragraph 0023; 0024

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