ChemicalBook CAS DataBase List 2,6-Dimethylphenol

2,6-Dimethylphenol synthesis

13synthesis methods

Product Name:2,6-Dimethylphenol
CAS Number:576-26-1
Molecular formula:C8H10O
Molecular Weight:122.16

From coal tar oil or coal hydrogenation.
Synthesis of 2,6-dimethylphenol: The gas-phase catalytic reaction of phenol and methanol is carried out, and then purified by rectification, and the product purity can reach more than 99%.
Selective phenol methylation to 2,6-dimethylphenol in a fluidized bed of iron-chromium mixed oxide catalyst with o–cresol circulation
Catalytic synthesis of 2,6-dimethylphenol from methanol and cyclohexanone over titanium oxide-supported vanadium oxide catalysts

4919-37-3 Synthesis

4919-37-3
131 suppliers
$23.00/1g

576-26-1
337 suppliers
$10.00/25g

Yield:576-26-1 80.3%

Reaction Conditions:

with decarboxylase; pH=6.5 at 25; for 15 h;Enzymatic reaction;

Steps:

1.2
(2) the 4 - hydroxy - 3, 5 - dimethyl benzoic acid 141g (0.85 μM) and a decarboxylase enzyme-producing strain obtained somatic added to the buffer solution, according to the reaction time 15h, the reaction temperature is 25 °C, the stirring rate 160r/min, buffer solution pH value is 6.5 biological catalytic decarboxylation, containing the product of the reaction of 2, 6 - dimethyl phenol, HPLC tracking conversion rate, after the end of the, filtering the filtrate, concentrated to dry, and distilled to obtain the finished product 98g, the yield of 80.3%, purity 99.6% (HPLC).

References:

Li Hong;Zhejiang Jiuxu Pharmaceutical Co., Ltd.;Pan Ziguo;Zheng Fangjun;Zhang Jintao;Chen Jingfang;Fan Lingling CN106588576, 2017, A Location in patent:Paragraph 0081-0086

608-28-6 Synthesis