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ChemicalBook CAS DataBase List 2,6-Dimethyl-2,5-heptadien-4-one
504-20-1

2,6-Dimethyl-2,5-heptadien-4-one synthesis

11synthesis methods
-

Yield:504-20-1 90%

Reaction Conditions:

with sodium isopropylate in isopropyl alcohol at 20 - 60; for 6 h;Reagent/catalyst;Solvent;Temperature;

Steps:

1.2; 2.2; 3.2; 4.2; 1.2; 2.2 Step 2

Add 1-nitroso 2,2,6,6-tetramethyl-piperidone (600g, 3.26mol) into a 10L three-necked flask,4.5L isopropanol, sodium isopropoxide (35g, 0.43mol),Control the temperature at 2060, stop the reaction after 6 hours,Distill out isopropanol under reduced pressure, add 600ml water to the concentrate,Extract with 1.2L of n-hexane, dry with anhydrous magnesium sulfate,Filter, distill off n-hexane under reduced pressure, freeze, filter,405 g of light yellow crystals were obtained (yield 90%, GC=99.71%).

References:

CN113354522,2021,A Location in patent:Paragraph 0042; 0044; 0046-0047; 0049-0050; 0052-0053; ...