2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID synthesis
- Product Name:2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID
- CAS Number:70097-13-1
- Molecular formula:C16H10N2O4
- Molecular Weight:294.26
Yield:70097-13-1 85%
Reaction Conditions:
Stage #1: indole-2,3-dionewith hexadecyltrimethylammonium hydroxide in lithium hydroxide monohydrate at 20; for 0.166667 h;Sonication;Green chemistry;Pfitzinger Quinoline Synthesis;
Stage #2: 1-(4-nitrophenyl)ethan-1-one in lithium hydroxide monohydrate at 35; for 2 h;Sonication;Green chemistry;Pfitzinger Quinoline Synthesis;Temperature;
References:
More, Priyanka A.;Shankarling, Ganapati S. [New Journal of Chemistry,2017,vol. 41,# 21,p. 12380 - 12383] Location in patent:supporting information
![3-hydroxy-3-[2-(4-nitrophenyl)-2-oxoethyl]-1,3-dihydro-2H-indol-2-one](/CAS/20180703/GIF/70097-11-9.gif)
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