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914299-13-1

2-(4-bromo-2-methylphenyl)pyrrolidine synthesis

3synthesis methods
3-(4-Bromo-2-methylbenzoyl)-1-ethenyl-2-pyrrolidinone

914299-11-9
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2-(4-bromo-2-methylphenyl)pyrrolidine

914299-13-1
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-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: hydrogenchloride / tetrahydrofuran; water; isopropyl alcohol / 14 h / Heating / reflux
2: sodium tetrahydroborate / methanol; acetic acid / 2.5 h / -60 - -40 °C

References:

WO2006/117669,2006,A1