ChemicalBook CAS DataBase List 2,3-Dihydroxynaphthalene

2,3-Dihydroxynaphthalene synthesis

7synthesis methods

Product Name:2,3-Dihydroxynaphthalene
CAS Number:92-44-4
Molecular formula:C10H8O2
Molecular Weight:160.17

2,3-Dihydroxynaphthalene is prepared by caustic fusion of 3-hydroxynaphthalene-2,6-disulfonic acid followed by treatment with dilute sulfuric acid under pressure, or by acid desulfonation of 2,3-dihydroxynaphthalene-6-sulfonic acid.

91-20-3 Synthesis

91-20-3
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$13.19/250mg

92-44-4
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$9.00/1g

Yield:92-44-4 83.8%

Reaction Conditions:

with 2,4,6-trimethylphenylcarbene copper;dihydrogen peroxide;trimethyldodecylammonium chloride in octane at 50; for 7 h;Reagent/catalyst;

Steps:

11 Example 2
In a 1000 ml three-necked flask, 512 g of n-octane was added, and then 128 g of naphthalene was added.2,4,6-trimethylphenylcarbene copper0.13g, 3.0g of tetrahexyl ammonium chloride, and the temperature is raised to 50 ° C under stirring.Then add hydrogen peroxide (concentration 30%) within 2 hours.After 500 g, the reaction was continued at 50 ° C for 5 hours to stop the reaction. The aqueous phase was extracted 3 times with 100 g of n-octane.Combine the organic phases. Taking the organic phase for liquid chromatography analysis,125.8 g (yield 78.6%) containing 2,3-dihydroxynaphthalene was shown.; The auxiliary agent is dodecyltrimethylammonium chloride, and the rest is the same as in Example 2. The yield of 2,3-dihydroxynaphthalene is83.8%.

References:

Nantong Bosheng Chemical Co., Ltd.;Hu Xingbang;Yuan Zhongfei;Huang Caihong CN108409542, 2018, A Location in patent:Paragraph 0021; 0023; 0025; 0027; 0029; 0031; 0033; 0035

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