天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 2,3-Dichloropyrazine
4858-85-9

2,3-Dichloropyrazine synthesis

10synthesis methods
-

Yield:-

Reaction Conditions:

with trichlorophosphate at 60; for 1 h;Heating / reflux;

Steps:

46.2
3-CHLOROPYRAZINE 1-oxide (D46, Step 1) (2.2 g, 16.9 MMOL) was added slowly to phosphorus oxychloride (10 ml) at 60 °C. When the addition was complete the mixture was heated at reflux for 60 minutes. The mixture was allowed to cool and poured into ice and solid sodium acetate (5 g). This was stirred until the ice had melted and then extracted with DICHLOROMETHANE. The DICHLOROMETHANE extracts were combined, washed with saturated sodium bicarbonate solution, water and brine. The organic portion was dried under sodium sulfate and evaporated in vacuo. The resulting residue was purified by column chromatography ELUTING with a mixture of ethyl acetate: hexane (1: 20) to afford the title compound (0.86 g). 'H NMR (CDCI3) 8.32 (2H, s).

References:

GLAXO GROUP LIMITED WO2004/56369, 2004, A1 Location in patent:Page/Page column 23

FullText

2,3-Dichloropyrazine Related Search: