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38568-21-7

2,2-DIBROMOHEXAFLUOROPROPANE synthesis

3synthesis methods
-

Yield:38568-21-7 100%

Reaction Conditions:

with ACF in chloroform-d1 at 25; for 2 h;Reagent/catalyst;

Steps:

Isomerization of 1,2-dibromohexafluoropropane into 2,2-dibromohexafluoropropane:

As an indication for the activity of thecatalyst this reaction is used, because only very strong Lewis acidsperform this reaction at 25 C [57]. ACF (25 mg) or ACF. Et3GeH(25 mg) were suspensed in 1,2-dibromohexafluoropropane(250 mL). After 2 h at 25 °C, CDCl3 was added and the isomerizationreaction was monitored by 19F NMR spectroscopy. For ACF,the measurement revealed 100% conversion in constrast to theACF . Et3GeH sample with 0% of conversion.

References:

Mei?ner, Gisa;Feist, Michael;Braun, Thomas;Kemnitz, Erhard [Journal of Organometallic Chemistry,2017,vol. 847,p. 234 - 241]

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