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219865-96-0

2-(2,4-Difluoro-phenoxy)-5-nitro-pyridine synthesis

1synthesis methods
4548-45-2 Synthesis
2-Chloro-5-nitropyridine

4548-45-2
543 suppliers
$6.00/5g

367-27-1 Synthesis
2,4-Difluorophenol

367-27-1
339 suppliers
$6.00/5g

2-(2,4-Difluoro-phenoxy)-5-nitro-pyridine

219865-96-0
16 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / acetone / Reflux
2: sodium sulfate / tetrahydrofuran; water / 2.5 h / 20 °C

References:

Makley, Leah N.;Johnson, Oleta T.;Ghanakota, Phani;Rauch, Jennifer N.;Osborn, Delaney;Wu, Taia S.;Cierpicki, Tomasz;Carlson, Heather A.;Gestwicki, Jason E. [Bioorganic and Medicinal Chemistry,2021,vol. 34]

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