N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-carboxamide synthesis
- Product Name:N-(4-methoxyphenyl)-2-oxo-2H-chromene-3-carboxamide
- CAS Number:1846-94-2
- Molecular formula:C17H13NO4
- Molecular Weight:295.29
Yield:1846-94-2 74%
Reaction Conditions:
Stage #1: 2-oxo-2H-chromene-3-carboxylic acidwith dmap;N-(3-dimethylaminopropyl)-N-ethylcarbodiimide in dichloromethane at 0; for 0.0833333 h;Inert atmosphere;
Stage #2: 4-methoxy-aniline in dichloromethane at 20; for 4 h;Inert atmosphere;
References:
Fonseca, André;Matos, Maria Jo?o;Vilar, Santiago;Kachler, Sonja;Klotz, Karl-Norbert;Uriarte, Eugenio;Borges, Fernanda [Chemical Biology and Drug Design,2018,vol. 91,# 1,p. 245 - 256]
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