Yield:-

Reaction Conditions:

with 2,4-dichlorophenoxyacetic acid dimethylamine

Steps:

46 N-[4-(3-Chloro-4-methylphenyl)-5-methylthiazol-2-yl]-(2-chloro-5-nitrophenyl)carboxamide

Example 46 N-[4-(3-Chloro-4-methylphenyl)-5-methylthiazol-2-yl]-(2-chloro-5-nitrophenyl)carboxamide The title compound (0.510 g) was obtained according to the procedure described in Example 1 using 2-amino-4-(3-chloro-4-methylphenyl)-5-methylthiazole (0.368 g), DMA (5 ml) and 2-chloro-5-nitrobenzoyl chloride (0.407 g). ¹H-NMR (400 MHz, DMSO-d₆, TMS): δ(ppm) 2.39 (3H, s), 2.52 (3H, s), 7.47-7.52 (2H, m), 7.64-7.69 (1H,m), 7.89 (1H, d, J=8.8 Hz), 8.36 (1H, dd, J=8.8, 2.8 Hz), 8.56 (1H, d, J=2.8 Hz).

References:

US2003/134859,2003,A1