ChemicalBook CAS DataBase List (S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde

(S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde synthesis

6synthesis methods

Product Name:(S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde
CAS Number:170985-84-9
Molecular formula:C11H14N2O2
Molecular Weight:206.24

81445-44-5
48 suppliers
$125.00/25 mg

624-84-0 Synthesis

624-84-0
245 suppliers
$10.00/1g

(S)-[2-(Benzyloxy)propylidene]hydrazinecarboxaldehyde

170985-84-9
52 suppliers
$125.00/500 mg

Yield: 86%

Reaction Conditions:

in methanol;toluene at 0 - 30; for 3 h;Green chemistry;

Steps:

1.3-3.3
3,9.31 g (0.15 mol) of formylhydrazine was dissolved in 150 ml of methanol, and after cooling to 0 ° C, 150 ml of a toluene solution in which 29.56 g (0.18 mol) of (S)-2-benzyloxypropanal was dissolved was added.After slowly raising the temperature to 25-30 ° C, the reaction was stirred at this temperature for 3 hours;After completion of the reaction, the solvent was removed by rotary evaporation, and 80 ml of ethyl acetate was added to the residue, and the mixture was stirred at 25-30 ° C for 2 hours, and the precipitate was filtered off. After the mother liquid was removed from ethyl acetate, 80 ml of petroleum ether was added to the mixture, 25-30 ° C After stirring for 2 hours, the precipitate was filtered off and dried to give the product (S)-N'-(2-benzyloxypropylidene)formylhydrazide.31.90 g (0.155 mol), yield 86%.

References:

Ningbo Xinji New Materials Technology Co., Ltd.;Shao Ning;Wang Chunchun CN109651187, 2019, A Location in patent:Paragraph 0034; 0037-0040; 0041; 0044; 0046; 0049

33106-32-0 Synthesis