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1010-59-9

3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione, sodium salt synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium hydroxide / water / 75 - 103 °C / Large scale
2: sodium isocyanate; acetic acid / water / 9 h / 58 - 62 °C / pH 5.5-5.6 / Large scale
3: sodium hydroxide / 1 h / 55 - 95 °C / pH 11 / Large scale

References:

CN103724348,2016,B