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ChemicalBook CAS DataBase List 1-METHYLQUINOLIUM METHYL SULFATE
38746-10-0

1-METHYLQUINOLIUM METHYL SULFATE synthesis

1synthesis methods
-

Yield:38746-10-0 100%

Reaction Conditions:

in acetonitrile at 40; for 24 h;

Steps:

Method A

General procedure: In a 30mL round bottomed flask, a mixtureof 8-methylquinoline (1.4 g, 10mmol) and dimethyl sulfate(2.5 g, 20mmol) was heated at 60 °C for 15 h. The precipitatedsolid was washed with THF (20 mL) to afford 1,8-dimethylquinoliniummethylsulfate 2a' (1.78 g, 6.6mmol, 66%) as a white solid. When other reaction conditions or substrates were used, reactions were conducted in a similar way.

References:

Iwai, Kento;Yokoyama, Soichi;Asahara, Haruyasu;Nishiwaki, Nagatoshi [Bulletin of the Chemical Society of Japan,2020,vol. 93,# 1,p. 50 - 57]