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113398-02-0

1-METHYL-1H-PYRROLE-2-CARBOHYDRAZIDE synthesis

4synthesis methods
23466-27-5 Synthesis
ethyl 1-methylpyrrole-2-carboxylate

23466-27-5
44 suppliers
$98.00/1g

1-METHYL-1H-PYRROLE-2-CARBOHYDRAZIDE

113398-02-0
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Yield:-

Reaction Conditions:

with hydrazine hydrate monohydrate in ethanol at 100;Sealed tube;

Steps:



General procedure: The ester was then solubilized in EtOH and treated with hydrazine, hydrate (5 equiv.). The mixture was refluxed overnight and solvents were evaporated. Diethyl ether was added and the formed precipitate was filtered and washed with the same solvent to yield the expected hydrazide compound as a powder.

References:

Gavara, Laurent;Legru, Alice;Verdirosa, Federica;Sevaille, Laurent;Nauton, Lionel;Corsica, Giuseppina;Mercuri, Paola Sandra;Sannio, Filomena;Feller, Georges;Coulon, Rémi;De Luca, Filomena;Cerboni, Giulia;Tanfoni, Silvia;Chelini, Giulia;Galleni, Moreno;Docquier, Jean-Denis;Hernandez, Jean-Fran?ois [Bioorganic Chemistry,2021,vol. 113,art. no. 105024] Location in patent:supporting information

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