1-Chloro-3-ethylbenzene synthesis
- Product Name:1-Chloro-3-ethylbenzene
- CAS Number:620-16-6
- Molecular formula:C8H9Cl
- Molecular Weight:140.61
136415-83-3
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$95.00/1g
620-16-6
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$60.00/500 mg
Yield:620-16-6 51 %Spectr.
Reaction Conditions:
with 5 mol% Pd/C in benzene-d6 at 130; for 24 h;Inert atmosphere;Molecular sieve;Sealed tube;
Steps:
General procedure B for decarbonylation of aliphatic aldehydes
General procedure: Dry glass reaction tube purged with argon and equipped with a magnetic stir bar was chargedwith molecular sieves (3-4 ?, 100 mg), aldehyde 1a (40 μL, 0.30 mmol), Pd/C (16 mg, 5 mol%Pd), and C6D6 (1 mL) and the sealed tube was heated at 130 °C for 24 h. The reaction mixturewas cooled to room temperature, filtered through a short pad of SiO2 to remove the catalyst, andthe SiO2 was washed with C6D6 (2 × 0.5 mL). Compound 2a was obtained, NMR yield: 78%,based on methyl benzoate as a standard.
References:
Ajda?i?, Vladimir;Nikoli?, Andrea;Kerner, Michael;Wipf, Peter;Opsenica, Igor M. [Synlett,2018,vol. 29,# 13,p. 1781 - 1785] Location in patent:supporting information
2039-85-2
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$11.00/1g
620-16-6
76 suppliers
$60.00/500 mg
766-83-6
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$9.00/1g
2039-85-2
169 suppliers
$11.00/1g
620-16-6
76 suppliers
$60.00/500 mg
74-85-1
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$79.00/11l
108-90-7
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$10.00/25G
620-16-6
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$60.00/500 mg
108-37-2
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$6.00/10g
811-49-4
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$113.00/100ml
620-16-6
76 suppliers
$60.00/500 mg