1-CHLORO-2,4,5-TRIFLUORO-3-TRIFLUOROMETHYL-BENZENE synthesis

1synthesis methods

Product Name:1-CHLORO-2,4,5-TRIFLUORO-3-TRIFLUOROMETHYL-BENZENE
CAS Number:122030-03-9
Molecular formula:C7HClF6
Molecular Weight:234.53

3-CHLORO-2,4,5,6-TETRAFLUOROBENZOTRIFLUORIDE

4284-09-7
41 suppliers
$231.00/25g

1,2,3,5-TETRAFLUORO-4-TRIFLUOROMETHYL-BENZENE

5360-82-7
34 suppliers
$330.00/10g

1-CHLORO-2,4,5-TRIFLUORO-3-TRIFLUOROMETHYL-BENZENE

122030-03-9
20 suppliers
$398.00/10g

Yield:122030-03-9 50.4 % Chromat. ，5360-82-7 22.2 % Chromat.

Reaction Conditions:

Stage #1: 1-trifluoromethyl-2,4,5,6-tetrafluoro-3-chlorobenzenewith 2-H-3-chlorohexafluorotoluene;tin(ll) chloride;zinc in N,N-dimethyl-formamide at 70; for 8 h;closed flask;
Stage #2: with hydrogenchloride in N,N-dimethyl-formamide;

References:

Krasnov, Vyacheslav I.;Vinogradov, Andrey S.;Platonov, Vyacheslav E. [Mendeleev Communications,2006,vol. 16,# 3,p. 168 - 170]