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ChemicalBook CAS DataBase List 1-(bromomethyl)-2-chloro-4-nitrobenzene
42533-63-1

1-(bromomethyl)-2-chloro-4-nitrobenzene synthesis

3synthesis methods
-

Yield:42533-63-1 248 mg

Reaction Conditions:

with N-Bromosuccinimide;dibenzoyl peroxide in tetrachloromethane at 80;

Steps:

18.1

Add 2-chloro-4-nitrotoluene (200mg, 1 equivalent), benzoyl peroxide (28mg, 0.1 equivalent), and N-bromosuccinimide (228mg, 1.1 equivalent) to 20ml of tetrachloride In carbonization, react overnight at 80°C in an oil bath. After the reaction was completed, the solvent was removed, and the crude product was subjected to column chromatography to obtain 248 mg of product.

References:

CN112010789,2020,A Location in patent:Paragraph 0102-0106