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98534-83-9

1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& synthesis

4synthesis methods
112055-38-6 Synthesis
ETHYL 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE

112055-38-6
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Yield:98534-83-9 90%

Reaction Conditions:

with water;sodium hydroxide in ethanol at 80; for 1 h;

References:

Acebrón-Garciá-De-Eulate, Marta;Mayol-Llinàs, Joan;Holland, Matthew T. O.;Kim, So Yeon;Brown, Karen P.;Marchetti, Chiara;Hess, Jeannine;Di Pietro, Ornella;Mendes, Vitor;Abell, Chris;Floto, R. Andres;Coyne, Anthony G.;Blundell, Tom L. [Journal of Medicinal Chemistry,2022,vol. 65,# 3,p. 2149 - 2173]

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