Yield:2232-12-4 90%

Reaction Conditions:

with sodium hypochlorite;iodine in acetic acid butyl ester;water at 10; for 2 h;Solvent;Reagent/catalyst;

Steps:

2
10.0g (0.078 mol) of 5,5-dimethylhydantoin and the iodine 19.8g (0.078 mol) were added to 500-ml glass flasks, and 150 ml of water and 35 ml of n-butyl acetate were added to them. It cooled at 10 degrees C or less in the ice bath, and the sodium hypochlorite aqueous solution 50.3g (0.078 mol) of 11% of available chlorine concentration was dropped below 10 degrees C. After the end of dropping, by stirring at the temperature for 2 hours, the reaction advanced so that it might be expressed with the reaction formula shown in chemical formula 3 like the working example 1, and the crystal deposited. 26.7g of 1,3-diiodo-5,5-dimethylhydantoin which is an object was obtained by drying under decompression the crystal obtained by filtering this precipitated crystal. Yield was 90%.26.7g of 1,3-diiodo-5,5-dimethylhydantoin which is an object was obtained by drying under decompression the crystal obtained by filtering this precipitated crystal. Yield was 90%.

References:

TohoEarthTechLtd.;Mima, Sumihiko JP5734124, 2015, B2 Location in patent:Paragraph 0050; 0051; 0052

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