1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA synthesis
- Product Name:1-(2-FLUORO-6-(TRIFLOROMETHYL)BENZYL)UREA
- CAS Number:830346-46-8
- Molecular formula:C9H8F4N2O
- Molecular Weight:236.17
In a 250 ml three-necked flask, 3.4 g of E6, 20 ml of water, 4.23 g of urea, and hydrochloric acid (12 mol / L, 2 ml) were added. After refluxing for 3 hours, the reaction solution was cooled to 4 ° C with an ice water bath, and filtered to obtain 3.78 g of a white solid ( Yield: 91%).
57-13-6
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239087-06-0
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830346-46-8
148 suppliers
$24.00/100mg
Yield:830346-46-8 91%
Reaction Conditions:
with hydrogenchloride in water; for 3 h;Reflux;
Steps:
13 Example 13Preparation of 1- [2-fluoro-6- (trifluoromethyl) benzyl] urea E7
In a 100ml reaction bottle, add 3.4g of E6, 20ml of water, 4.23g of urea,And hydrochloric acid (12mol / L, 2ml), and reacted under reflux for 3h, the reaction solution was cooled to 4 ° C with an ice water bath, and filtered with suctionThere was obtained 3.78 g of a white solid (yield 91%).
References:
CN110498771,2019,A Location in patent:Paragraph 0137-0139
57-13-6
713 suppliers
$5.00/5g
239087-08-2
205 suppliers
$14.00/1g
830346-46-8
148 suppliers
$24.00/100mg
60611-24-7
202 suppliers
$10.00/1g
830346-46-8
148 suppliers
$24.00/100mg