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ChemicalBook CAS DataBase List 1,2-Dimethylimidazole
1739-84-0

1,2-Dimethylimidazole synthesis

10synthesis methods
-

Yield:1739-84-0 85%

Reaction Conditions:

in N,N-dimethyl-formamide at 120 - 145;Solvent;Temperature;

Steps:

2 Example 2
To 500 ml of the input three-mouth flask in 128g of 2 - methyl imidazole and 100 ml of DMF, oil bath heated to 120 °C, the temperature next adds by drops 280g dimethyl carbonate, control temperature at 135 - 140 °C, dropping time control in 5 - 6h, after dropping in the 145 °C preserving 2h, thermal insulation after the completion of the, gas chromatographic analysis of 2 - methyl imidazole conversion 98%. In 4.0KPa, 90 °C conditions under reduced pressure distillation, evaporate the solvent. The use of the rectifying device, in 4.0KPa under vacuum, collecting 100 - 110 °C of distillate, high purity can be obtained of the 1, 2 - dimethyl imidazole of the finished product, yield 85%, gas chromatographic analysis of the content of 99.5%.

References:

Jiangsu Leisure New Material Technology Co., Ltd;Xia, Wei;Shen, Jian;Wang, Koojun;Yan, Yong CN106045912, 2016, A Location in patent:Paragraph 0020; 0021; 0023; 0024; 0025; 0026; 0027

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