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ChemicalBook >> CAS DataBase List >> YM155

YM155

YM155 price.
  • $28 - $2395.3
  • Product name: YM155
  • CAS: 781661-94-7
  • MF: C20H19BrN4O3
  • MW: 443.29386
  • EINECS:-0
  • MDL Number:MFCD11983133
  • Synonyms:YM155;4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide;SepantroniuM broMide;SepantroniuM broMide(YM155,YM-155);Sepantronium Bromide (YM155);1H-Naphth[2,3-d]imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-, bromide (1:1);4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide YM 155;YM 155 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium bromide
43 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1unit
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 10
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberSYN5758
  • Product descriptionYM155
  • Packaging100mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging5mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging10mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging50mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging100mg
  • Price$247
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging250mg
  • Price$371
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA307284
  • Product descriptionYM-155 98+%
  • Packaging1g
  • Price$928
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004446
  • Product descriptionYM-155 95.00%
  • Packaging5MG
  • Price$526
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004446
  • Product descriptionYM-155 95.00%
  • Packaging10MG
  • Price$594.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004446
  • Product descriptionYM-155 95.00%
  • Packaging25MG
  • Price$887
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging10mM(in 1mL DMSO)
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging25mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4221
  • Product descriptionYM155
  • Packaging100mg
  • Price$470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5758 YM155 100mg $931 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 5mg $41 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 10mg $57 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 50mg $154 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 100mg $247 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 250mg $371 2021-12-16 Buy
Ambeed A307284 YM-155 98+% 1g $928 2021-12-16 Buy
American Custom Chemicals Corporation INB0004446 YM-155 95.00% 5MG $526 2021-12-16 Buy
American Custom Chemicals Corporation INB0004446 YM-155 95.00% 10MG $594.8 2021-12-16 Buy
American Custom Chemicals Corporation INB0004446 YM-155 95.00% 25MG $887 2021-12-16 Buy
ApexBio Technology A4221 YM155 1unit $28 2021-12-16 Buy
ApexBio Technology A4221 YM155 5mg $50 2021-12-16 Buy
ApexBio Technology A4221 YM155 10mM(in 1mL DMSO) $66 2021-12-16 Buy
ApexBio Technology A4221 YM155 10mg $85 2021-12-16 Buy
ApexBio Technology A4221 YM155 25mg $190 2021-12-16 Buy
ApexBio Technology A4221 YM155 100mg $470 2021-12-16 Buy

Properties

Melting point :>180°C (dec.)
storage temp. :-20°
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
color :Tan to yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Survivin, a member of the inhibitor of apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in many types of cancer. YM-155 is a novel small molecule that suppresses transactivation of survivin through direct binding to its promoter. It selectively suppresses expression of survivin and induces apoptosis in p53-deficient cancer cells in vitro at 10 nM. At concentrations up to 100 nM, YM-155 has little effect on expression levels of other IAP- or Bcl-2-related proteins. YM-155 exerts anti-tumor effects in various in vivo cancer models, including prostate, pancreatic, and lung cancer.

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