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ChemicalBook >> CAS DataBase List >> Warfarin

Warfarin

Warfarin price.
  • $19 - $2055.9
  • Product name: Warfarin
  • CAS: 81-81-2
  • MF: C19H16O4
  • MW: 308.33
  • EINECS:201-377-6
  • MDL Number:MFCD00006854
  • Synonyms:SAKARAT;PROLIN(R);WARF COMPOUND 42(R);WARF(R);Warfarat;WARFARIN;KYPFARIN(R);DL-3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN
13 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 100ug
  • 100ul
  • 200mg
  • 250mg
  • 1G
  • 5G
  • 10G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004609
  • Product descriptionWARFARIN 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004609
  • Product descriptionWARFARIN 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13566
  • Product description(±)-Warfarin ≥98%
  • Packaging1g
  • Price$23
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9053
  • Product descriptionWarfarin >98%
  • Packaging1g
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number14187
  • Product descriptionWarfarin
  • Packaging5G
  • Price$1880
  • Updated2021-12-16
  • Buy
  • ManufacturerOakwood
  • Product number245858
  • Product descriptionWarfarin 99%
  • Packaging250mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerOakwood
  • Product number245858
  • Product descriptionWarfarin 99%
  • Packaging1g
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1719000
  • Product descriptionWarfarin? United States Pharmacopeia (USP) Reference Standard
  • Packaging200mg
  • Price$436
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA2250
  • Product descriptionWarfarin? analytical standard
  • Packaging10g
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number45706
  • Product descriptionWarfarin PESTANAL?, analytical standard
  • Packaging250mg
  • Price$58.4
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberW498500
  • Product descriptionWarfarin
  • Packaging1g
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number490150
  • Product descriptionRAX
  • Packaging100ul
  • Price$499
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number132364
  • Product descriptionRAX
  • Packaging100ug
  • Price$539
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0004609 WARFARIN 95.00% 1G $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0004609 WARFARIN 95.00% 10G $2055.9 2021-12-16 Buy
Cayman Chemical 13566 (±)-Warfarin ≥98% 1g $23 2024-03-01 Buy
DC Chemicals DC9053 Warfarin >98% 1g $300 2021-12-16 Buy
Medical Isotopes, Inc. 14187 Warfarin 5G $1880 2021-12-16 Buy
Oakwood 245858 Warfarin 99% 250mg $19 2021-12-16 Buy
Oakwood 245858 Warfarin 99% 1g $30 2021-12-16 Buy
Sigma-Aldrich 1719000 Warfarin? United States Pharmacopeia (USP) Reference Standard 200mg $436 2024-03-01 Buy
Sigma-Aldrich A2250 Warfarin? analytical standard 10g $151 2024-03-01 Buy
Sigma-Aldrich 45706 Warfarin PESTANAL?, analytical standard 250mg $58.4 2024-03-01 Buy
TRC W498500 Warfarin 1g $110 2021-12-16 Buy
Usbiological 490150 RAX 100ul $499 2021-12-16 Buy
Usbiological 132364 RAX 100ug $539 2021-12-16 Buy

Properties

Melting point :162-164 °C(lit.)
Boiling point :356°C
Density :1.1411 (rough estimate)
vapor pressure :0.09 at 22 °C (NIOSH, 1997)
refractive index :1.4434 (estimate)
Flash point :2℃
storage temp. :2-8°C
solubility :Soluble in benzene, 1,4-dioxane (Weast, 1986), and acetone (Sax and Lewis, 1987). Moderately soluble in methanol, ethanol, isopropanol, and some oils (Windholz et al., 1983). Also soluble in toluene.
form :Crystalline
pka :pKa 4.90±0.01(H2O t = 25±0.5 I = 0.15 (KCl))(Approximate)
color :Colorless
Odor :odorless
Water Solubility :Practically insoluble
Merck :13,10097
BRN :8868198
Exposure limits :NIOSH REL: TWA 0.1 mg/m3, IDLH 100 mg/m3; OSHA PEL: 0.1 mg/m3; ACGIH TLV: TWA 0.1 mg/m3.
LogP :2.600
CAS DataBase Reference :81-81-2(CAS DataBase Reference)
NIST Chemistry Reference :3-(Alpha-acetonylbenzyl)-4-hydroxycoumarin(81-81-2)
EPA Substance Registry System :Warfarin (81-81-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Warfarin is tasteless and colorless. It is a widely used as anticoagulant (which stops the blood clotting) in the treatment and prevention of thrombosis, in the treatment for chronic atrial fibrillation, mechanical valves, pulmonary embolism, and dilated cardiomyopathy. Warfarin is metabolized primarily via oxidation in the liver by CYP2C9, and exerts its anticoagulant effect by inhibiting the protein vitamin K epoxide reductase complex, subunit 1 (VKORC1). Warfarin therapy can be associated with significant bleeding complications. Achieving a safe therapeutic response can be difficult because of warfarin’s narrow therapeutic index and great individual variability in the dose required, which is mostly a consequence of individual genetic variants: it is influenced by ageing, co-prescribed drugs, diet, alcohol consumption, and comorbid conditions. To maintain a therapeutic level of anti-thrombosis and to minimize the risk of bleeding complications, warfarin therapy requires intensive monitoring via the INR to guide its dosing. It is also used as the first generation of anticoagulant rodenticides.

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