Vorapaxar
|
- $28 - $2000
- Product name: Vorapaxar
- CAS: 618385-01-6
- MF: C29H33FN2O4
- MW: 492.58
- EINECS:
- MDL Number:MFCD16038876
- Synonyms:Vorapaxar;Vorapaxar (SCH 530348);Voarapaxar;Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate;[(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-me;Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester;CS-1663;CS-2015
21 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 1unit
- 10mM(in 1mL DMSO)
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product numberY1927
- Product descriptionVorapaxar
- Packaging1mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ96880
- Product descriptionVorapaxar
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ96880
- Product descriptionVorapaxar
- Packaging25mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007774
- Product descriptionVORAPAXAR 95.00%
- Packaging5MG
- Price$341
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging5mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging10mM(in 1mL DMSO)
- Price$141
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging10mg
- Price$252
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging25mg
- Price$475
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8809
- Product descriptionVorapaxar
- Packaging50mg
- Price$713
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23119
- Product descriptionVorapaxar ≥98%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23119
- Product descriptionVorapaxar ≥98%
- Packaging5mg
- Price$208
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM141596
- Product description[(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-carbamicacidethylester 98%
- Packaging50mg
- Price$491
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5527
- Product descriptionVorapaxar 99.85%
- Packaging5mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5527
- Product descriptionVorapaxar 99.85%
- Packaging10mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5527
- Product descriptionVorapaxar 99.85%
- Packaging25mg
- Price$600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1927 | Vorapaxar | 1mg | $51 | 2021-12-16 | Buy |
| AK Scientific | J96880 | Vorapaxar | 10mg | $288 | 2021-12-16 | Buy |
| AK Scientific | J96880 | Vorapaxar | 25mg | $600 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0007774 | VORAPAXAR 95.00% | 5MG | $341 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 5mg | $137 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 10mM(in 1mL DMSO) | $141 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 10mg | $252 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 25mg | $475 | 2021-12-16 | Buy |
| ApexBio Technology | A8809 | Vorapaxar | 50mg | $713 | 2021-12-16 | Buy |
| Cayman Chemical | 23119 | Vorapaxar ≥98% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 23119 | Vorapaxar ≥98% | 5mg | $208 | 2024-03-01 | Buy |
| Chemenu | CM141596 | [(1R,3AR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-carbamicacidethylester 98% | 50mg | $491 | 2021-12-16 | Buy |
| ChemScene | CS-5527 | Vorapaxar 99.85% | 5mg | $168 | 2021-12-16 | Buy |
| ChemScene | CS-5527 | Vorapaxar 99.85% | 10mg | $288 | 2021-12-16 | Buy |
| ChemScene | CS-5527 | Vorapaxar 99.85% | 25mg | $600 | 2021-12-16 | Buy |
Properties
Boiling point :676.0±55.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥24.65 mg/mL in DMSO; insoluble in H2O; ≥10.64 mg/mL in EtOH with ultrasonic
form :solid
pka :12.49±0.60(Predicted)
color :White to off-white
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :Store at -20° C
solubility :≥24.65 mg/mL in DMSO; insoluble in H2O; ≥10.64 mg/mL in EtOH with ultrasonic
form :solid
pka :12.49±0.60(Predicted)
color :White to off-white
Safety Information
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Description
Vorapaxar is an orally bioavailable competitive antagonist of the proteinase-activated receptor (PAR1; Ki = 8.1 nM), also known as the thrombin receptor. It is selective for PAR1 over other PARs, as well as a number of GPCRs, ion channels, and receptors. It inhibits platelet aggregation induced by thrombin and haTRAP (IC50s = 47 and 25 nM, respectively). Vorapaxar (0.1 mg/kg, i.v.) completely inhibits platelet aggregation in cynomolgus monkeys ex vivo. Formulations containing vorapaxar are used in the prevention of thrombotic cardiovascular events.Related product price
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