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ChemicalBook >> CAS DataBase List >> Vasicine

Vasicine

Vasicine price.
  • $45 - $1200
  • Product name: Vasicine
  • CAS: 6159-55-3
  • MF: C11H12N2O
  • MW: 188.23
  • EINECS:228-180-8
  • MDL Number:MFCD01544498
  • Synonyms:1-b)quinazolin-3-ol,1,2,3,9-tetrahydro-pyrrolo( ;vasicin ;AKOS NCG1-0080;VITAS-BB TBB000541;VASICINE;C10733;HARMALINE HCL(RG);(3R)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-3-ol
9 prices
Selected condition:
Brand
  • A1 Biochem Labs
  • AK Scientific
  • Arctom
  • Cayman Chemical
  • CSNpharm
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerA1 Biochem Labs
  • Product numberA1-06843
  • Product descriptionPeganine 95%
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1716
  • Product descriptionVasicine
  • Packaging1mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN97052
  • Product descriptionVasicine ≥98%
  • Packaging5mg
  • Price$218
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11760
  • Product descriptionVasicine ≥95%
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11760
  • Product descriptionVasicine ≥95%
  • Packaging5mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11760
  • Product descriptionVasicine ≥95%
  • Packaging10mg
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12193
  • Product descriptionVasicine
  • Packaging1mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN12193
  • Product descriptionVasicine
  • Packaging5mg
  • Price$434
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT304240
  • Product description1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol
  • Packaging50mg
  • Price$155
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A1 Biochem Labs A1-06843 Peganine 95% 100mg $1200 2021-12-16 Buy
AK Scientific V1716 Vasicine 1mg $160 2021-12-16 Buy
Arctom CFN97052 Vasicine ≥98% 5mg $218 2021-12-16 Buy
Cayman Chemical 11760 Vasicine ≥95% 1mg $45 2021-12-16 Buy
Cayman Chemical 11760 Vasicine ≥95% 5mg $191 2021-12-16 Buy
Cayman Chemical 11760 Vasicine ≥95% 10mg $324 2021-12-16 Buy
CSNpharm CSN12193 Vasicine 1mg $174 2021-12-16 Buy
CSNpharm CSN12193 Vasicine 5mg $434 2021-12-16 Buy
TRC T304240 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-ol 50mg $155 2021-12-16 Buy

Properties

Melting point :211.5°C
Boiling point :323.23°C (rough estimate)
Density :1.1124 (rough estimate)
refractive index :1.5850 (estimate)
solubility :DMSO : 83.33 mg/mL (442.70 mM; Need ultrasonic)
form :Powder
pka :13.08±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

This quinazoline alkaloid was first isolated from the leaves of Adhatoda vasica Nees by Hooper and subsequently discovered in Peganum harmala under the name Peganine. The base is optically inactive although Spath and Kesztler have reported the isolation of the (-)-form from the fresh leaves of A. vasica and Rosenfeld and Kolesnikow have obtained the same form from the flowers and stems of Peganum harmala. The salts are readily obtained crystalline, e.g. the hydrochloride dihydrate, m.p. 208°C (dry); hydriodide dihydrate, m.p. 195°C (dry); picrate, m.p. 199°C (dec.) and the methiodide, m.p. 187°C.
With AcOH, the alkaloid gives an anomalous acetyl derivative, m.p. 165°C, subsequently shown to be N-acetylpedadiene. Oxidation with KMn04 gives 4-quinazolone and 4-keto-3 :4-dihydroxyquinazolyl-3-acetic acid, the latter characterized as the methyl ester, m.p. 152°C.
The crude drug from A. vasica is used in India as a remedy for asthma while the pure alkaloid acts as a bronchodilator.

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