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ChemicalBook >> CAS DataBase List >> Treprostinil

Treprostinil

Treprostinil  price.
  • $97 - $34072.5
  • Product name: Treprostinil
  • CAS: 81846-19-7
  • MF: C23H34O5
  • MW: 390.51
  • EINECS:808-233-7
  • MDL Number:MFCD00888847
  • Synonyms:2-[[[(1R,2R,3aS,9aS)-2α-Hydroxy-1β-[(S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indene]-5-yl]oxy]acetic acid;UT-15;[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid;Treprostinil Sodium intermediate;[1R-[1α(S*),2β,3aα,9aα]]-;2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic Acid;Acetic acid, 2-[[(1R,2R,3aS,9aS)-2,3,3a,4,9,9a-hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]-;REMODULIN
20 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 2mg
  • 25mg
  • 0.025g
  • 10
  • 1MG
  • 5mg
  • 10mg
  • 100mg
  • 250mg
  • 1G
  • ManufacturerAHH
  • Product numberMT-58412
  • Product descriptionRemodulin 98%
  • Packaging0.025g
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2025AH
  • Product descriptionRemodulin
  • Packaging10mg
  • Price$523
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004481
  • Product descriptionTREPROSTINIL 95.00%
  • Packaging1MG
  • Price$202.65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004481
  • Product descriptionTREPROSTINIL 95.00%
  • Packaging1G
  • Price$34072.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573008
  • Product descriptionTreprostinil free acid >98%
  • Packaging100mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573008
  • Product descriptionTreprostinil free acid >98%
  • Packaging250mg
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573008
  • Product descriptionTreprostinil free acid >98%
  • Packaging1g
  • Price$3876
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10162
  • Product descriptionTreprostinil ≥98%
  • Packaging1mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10162
  • Product descriptionTreprostinil ≥98%
  • Packaging5mg
  • Price$433
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10162
  • Product descriptionTreprostinil ≥98%
  • Packaging10mg
  • Price$768
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7872
  • Product descriptionTreprostinil 99.98%
  • Packaging2mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7872
  • Product descriptionTreprostinil 99.98%
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7872
  • Product descriptionTreprostinil 99.98%
  • Packaging10mg
  • Price$354
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-7872
  • Product descriptionTreprostinil 99.98%
  • Packaging25mg
  • Price$792
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12028777
  • Product descriptionRumodolin 97%
  • Packaging1g
  • Price$980
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN23716
  • Product descriptionRumodolin
  • Packaging10mg
  • Price$235
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-58412 Remodulin 98% 0.025g $790 2021-12-16 Buy
AK Scientific 2025AH Remodulin 10mg $523 2021-12-16 Buy
American Custom Chemicals Corporation API0004481 TREPROSTINIL 95.00% 1MG $202.65 2021-12-16 Buy
American Custom Chemicals Corporation API0004481 TREPROSTINIL 95.00% 1G $34072.5 2021-12-16 Buy
Biorbyt Ltd orb573008 Treprostinil free acid >98% 100mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb573008 Treprostinil free acid >98% 250mg $1949.9 2021-12-16 Buy
Biorbyt Ltd orb573008 Treprostinil free acid >98% 1g $3876 2021-12-16 Buy
Cayman Chemical 10162 Treprostinil ≥98% 1mg $97 2024-03-01 Buy
Cayman Chemical 10162 Treprostinil ≥98% 5mg $433 2024-03-01 Buy
Cayman Chemical 10162 Treprostinil ≥98% 10mg $768 2024-03-01 Buy
ChemScene CS-7872 Treprostinil 99.98% 2mg $132 2021-12-16 Buy
ChemScene CS-7872 Treprostinil 99.98% 5mg $252 2021-12-16 Buy
ChemScene CS-7872 Treprostinil 99.98% 10mg $354 2021-12-16 Buy
ChemScene CS-7872 Treprostinil 99.98% 25mg $792 2021-12-16 Buy
Crysdot CD12028777 Rumodolin 97% 1g $980 2021-12-16 Buy
CSNpharm CSN23716 Rumodolin 10mg $235 2021-12-16 Buy

Properties

Melting point :121-123°
Boiling point :587.1±50.0 °C(Predicted)
Density :1.158±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :Chloroform (Slightly, Heated), Methanol (Slightly, Heated)
form :Solid
pka :3.19±0.10(Predicted)
color :Off-White to Beige
InChIKey :PAJMKGZZBBTTOY-ZFORQUDYSA-N
SMILES :C(O)(=O)COC1=C2C(=CC=C1)C[C@@]1([H])[C@@]([H])(C2)C[C@@H](O)[C@@H]1CC[C@@H](O)CCCCC

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Primary pulmonary hypertension (PPH) is a condition of unknown cause that is characterized by increasing pulmonary arterial and vascular resistance. Treprostinil is a stable analog of prostacyclin that is used clinically for the treatment of PPH under the trade name Remodulin?. The structural modifications in treprostinil compared to prostacyclin increase the plasma half-life from 2 minutes to 34 and 85 minutes for intravenous and subcutaneous infusion of the drug, respectively. In addition to treprostinil’s direct vasodilatory effects, it also inhibits inflammatory cytokine (TNFα, IL-1β, IL-6, GM-CF) production by human alveolar macrophages in the sub-micromolar range by preventing NF-κB translocation to the nucleus.

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