Trelagliptin
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- $49 - $1208.7
- Product name: Trelagliptin
- CAS: 865759-25-7
- MF: C18H20FN5O2
- MW: 357.38
- EINECS:1592732-453-0
- MDL Number:MFCD22572746
- Synonyms:Trelagliptin(syr472);Benzonitrile, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H) -pyrimidinyl]methyl]-4-fluoro-;Trelagliptin (R)-2-[[6-(3-Aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl]methyl]-4-fluorobenzonitrile;(S)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile;Trelagliptin Isomer Impurity;Trelagliptin, >=98%;Trelagliptin free base;Trelagliptin
24 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Ark Pharm
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- ManufacturerAK Scientific
- Product number2763AH
- Product descriptionTrelagliptin
- Packaging10mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3888
- Product descriptionTrelagliptin
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000057192
- Product descriptionTrelagliptin 98+%
- Packaging1mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000057192
- Product descriptionTrelagliptin 98+%
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000057192
- Product descriptionTrelagliptin 98+%
- Packaging10mg
- Price$137
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000057192
- Product descriptionTrelagliptin 98+%
- Packaging50mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181339
- Product descriptionTrelagliptin >98%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181339
- Product descriptionTrelagliptin >98%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181339
- Product descriptionTrelagliptin >98%
- Packaging1000mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18504
- Product descriptionTrelagliptin ≥98%
- Packaging1mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18504
- Product descriptionTrelagliptin ≥98%
- Packaging5mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18504
- Product descriptionTrelagliptin ≥98%
- Packaging10mg
- Price$388
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1041
- Product descriptionTrelagliptin 99.80%
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1041
- Product descriptionTrelagliptin 99.80%
- Packaging10mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1041
- Product descriptionTrelagliptin 99.80%
- Packaging50mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1041
- Product descriptionTrelagliptin 99.80%
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2763AH | Trelagliptin | 10mg | $166 | 2021-12-16 | Buy |
| ApexBio Technology | A3888 | Trelagliptin | 5mg | $80 | 2021-12-16 | Buy |
| Ark Pharm | P000057192 | Trelagliptin 98+% | 1mg | $52 | 2021-12-16 | Buy |
| Ark Pharm | P000057192 | Trelagliptin 98+% | 5mg | $85 | 2021-12-16 | Buy |
| Ark Pharm | P000057192 | Trelagliptin 98+% | 10mg | $137 | 2021-12-16 | Buy |
| Ark Pharm | P000057192 | Trelagliptin 98+% | 50mg | $550 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181339 | Trelagliptin >98% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181339 | Trelagliptin >98% | 250mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181339 | Trelagliptin >98% | 1000mg | $1208.7 | 2021-12-16 | Buy |
| Cayman Chemical | 18504 | Trelagliptin ≥98% | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 18504 | Trelagliptin ≥98% | 5mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 18504 | Trelagliptin ≥98% | 10mg | $388 | 2024-03-01 | Buy |
| ChemScene | CS-1041 | Trelagliptin 99.80% | 5mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-1041 | Trelagliptin 99.80% | 10mg | $80 | 2021-12-16 | Buy |
| ChemScene | CS-1041 | Trelagliptin 99.80% | 50mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-1041 | Trelagliptin 99.80% | 100mg | $160 | 2021-12-16 | Buy |
Properties
Boiling point :519.0±60.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥11.6 mg/mL in DMSO; ≥3.68 mg/mL in EtOH with gentle warming and ultrasonic; ≥93.8 mg/mL in H2O
form :solid
pka :9.88±0.20(Predicted)
color :White to off-white
InChI :InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1
InChIKey :IWYJYHUNXVAVAA-OAHLLOKOSA-N
SMILES :C(#N)C1=CC=C(F)C=C1CN1C(=O)N(C)C(=O)C=C1N1CCC[C@@H](N)C1
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥11.6 mg/mL in DMSO; ≥3.68 mg/mL in EtOH with gentle warming and ultrasonic; ≥93.8 mg/mL in H2O
form :solid
pka :9.88±0.20(Predicted)
color :White to off-white
InChI :InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1
InChIKey :IWYJYHUNXVAVAA-OAHLLOKOSA-N
SMILES :C(#N)C1=CC=C(F)C=C1CN1C(=O)N(C)C(=O)C=C1N1CCC[C@@H](N)C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Dipeptidyl peptidase 4 (DPP-4) is an intrinsic membrane glycoprotein that acts as an exopeptidase, cleaving oligopeptides after the second amino acid from the N-terminal end. One of its substrates is glucagon-like peptide 1, an incretin that stimulates insulin biosynthesis and secretion while inhibiting glucagon release in a glucose-dependent manner. Trelagliptin is a pyrimidinedione-based, long-acting inhibitor of DPP-4 (IC50 = 4 nM). It demonstrates >10,000-fold selectivity over other peptidases. Trelagliptin has been used to improve glucose tolerance and postprandial plasma insulin levels in Zucker fa/fa rats. In 2014 this compound underwent phase III clinical trials.More related product prices
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